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THE SILVEC SOLUTION

TREE DISEASE & TREATMENT
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Why tree diseases matter

  • Trees, vines, and bushes produce 20% of agricultural products

  • Pathogens cause over $100 billion of annual damage

  • Increasing orchard productivity is essential to feeding the world

  • Many pathogen threats are currently incurable and indefensible

The reason for lack of treatment

  • Plants lack a circulatory system capable of delivering anti-pathogenic agents to infected cells – without a delivery method, there can no treatment for sick trees

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GMO seed solutions are not well suited for trees

  • Costly with fruit iterations taking years

  • Requires replanting

  • Drastically reduces the varieties available

  • Can alter fruit taste and can face consumer rejection

  • Only one GMO tree fully commercialized over past several decades (papaya)

Silvec has developed the first method for vaccinating trees using breakthrough innovation

PROPRIETARY RNA THERAPY

Silvec discovered a new type of RNA (iRNA) that it engineers to induce trees to generate compounds able to vaccinate against or cure most diseases

It’s a revolution for tree disease treatment
similar to the invention of vaccines & antibiotics for humans

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1796

1928

2020

Animal virus (smallpox) first defeated by Jenner

Animal bacteria first defeated

by Fleming (penicillin)

Plant virus first defeated

by Silvec

 THE SILVEC PROCESS 

Step 1: Introduce vector

iRNAs are the only known safe and effective delivery vector for mature trees

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Step 2: Design insert

Novel process for developing insert(s) that generate beneficial products targeting specific pathogens or gene expression

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Step 3: Integrate insert

Integrate insert(s) into vector without impacting its performance using novel stabilization processes

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Step 4: Package budwood

Use iRNA infected “mother trees” as a factory to produce millions of budwood for grafting into mature trees or seedlings

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Step 5: Graft on to tree

End-users to graft budwood into trees in minutes to introduce the iRNA into the tree’s phloem to infect cells systemically

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Step 6: Sustained benefits

iRNA replicates continuously in tree producing anti-pathogenic products throughout its lifespan from a single graft

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PROVEN RESULTS

Silvec has proven the RNA therapy by vaccinating hundreds of plants

against a deadly tree virus with near 100% efficacy

Control group shows infection with deadly virus (green)

Silvec immunized plants remain healthy (red)

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"PLUG & PLAY" PLATFORM

Silvec's platform innovation can be used to develop solutions for most any tree to protect against disease or introduce other beneficial traits

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