THE SILVEC SOLUTION
TREE DISEASE & TREATMENT
Why tree diseases matter
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Trees, vines, and bushes produce 20% of agricultural products
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Pathogens cause over $100 billion of annual damage
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Increasing orchard productivity is essential to feeding the world
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Many pathogen threats are currently incurable and indefensible
The reason for lack of treatment
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Plants lack a circulatory system capable of delivering anti-pathogenic agents to infected cells – without a delivery method, there can no treatment for sick trees
GMO seed solutions are not well suited for trees
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Costly with fruit iterations taking years
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Requires replanting
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Drastically reduces the varieties available
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Can alter fruit taste and can face consumer rejection
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Only one GMO tree fully commercialized over past several decades (papaya)
Silvec has developed the first method for vaccinating trees using breakthrough innovation
PROPRIETARY RNA THERAPY
Silvec discovered a new type of RNA (iRNA) that it engineers to induce trees to generate compounds able to vaccinate against or cure most diseases
It’s a revolution for tree disease treatment
similar to the invention of vaccines & antibiotics for humans
1796
1928
2020
Animal virus (smallpox) first defeated by Jenner
Animal bacteria first defeated
by Fleming (penicillin)
Plant virus first defeated
by Silvec
THE SILVEC PROCESS
Step 1: Introduce vector
iRNAs are the only known safe and effective delivery vector for mature trees
Step 2: Design insert
Novel process for developing insert(s) that generate beneficial products targeting specific pathogens or gene expression
Step 3: Integrate insert
Integrate insert(s) into vector without impacting its performance using novel stabilization processes
Step 4: Package budwood
Use iRNA infected “mother trees” as a factory to produce millions of budwood for grafting into mature trees or seedlings
Step 5: Graft on to tree
End-users to graft budwood into trees in minutes to introduce the iRNA into the tree’s phloem to infect cells systemically
Step 6: Sustained benefits
iRNA replicates continuously in tree producing anti-pathogenic products throughout its lifespan from a single graft
PROVEN RESULTS
Silvec has proven the RNA therapy by vaccinating hundreds of plants
against a deadly tree virus with near 100% efficacy
Control group shows infection with deadly virus (green)
Silvec immunized plants remain healthy (red)
"PLUG & PLAY" PLATFORM
Silvec's platform innovation can be used to develop solutions for most any tree to protect against disease or introduce other beneficial traits
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